The meniscus is a “C”-shaped cartilage that acts as a shock absorber for the cartilage on the surface of the bone. Tears of the meniscus usually occur as a result of a twisting injury, but may occur due to repetitive trauma, arthritis and increased age. Symptoms are often intermittent depending on activity and can include pain, swelling, popping and catching and tend to be worse with squatting, kneeling and impact activity.
In a study published in the Journal of Bone and Joint Surgery, Vangsness et al. reported results in 35 patients who underwent partial meniscus removal and were randomized to either receive stem cell or sodium hyaluronate injection (control group). Patients in the stem cell group regenerated new meniscus, where no patients in the sodium hylauronate group formed new meniscus. Patients who received stem cell injection also had a significant decrease in pain compared to the control group. Review Study
Vangsness CT, Farr J, Boyd J, Dellaero DT, Mills CR, LeRouxWilliams M (2014) Adult human mesenchymal stem cells derived via intra- articular injection to the knee following partial medial meniscectomy: a randomized, doubleblind controlled study. J Bone Joint Surg Am (96)2: 90-98